China (Mainland)
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Gefitinib CAS NO.184475-35-2
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
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Quick Details
- ProName: Gefitinib
- CasNo: 184475-35-2
- Molecular Formula: C22H24ClFN4O3
- Appearance: light-yellow crystalline powder
- Application: Gefitinib (Iressa, ZD-1839) is an EGFR...
- DeliveryTime: 15 days after order confirmed
- PackAge: 100g/bottle,1kg/bottle,25kg/drum or as...
- Port: Shanghai, Ningbo, Tianjin, etc
- ProductionCapacity: 100 Kilogram/Month
- Purity: 99%
- Storage: Stored in cool, dry and ventilation pl...
- Transportation: by courier door to door or by sea
- LimitNum: 1 Kilogram
Superiority
Superior quality, moderate price & quick delivery.
Details
| Gefitinib Chemical Properties |
| mp | 119-1200C |
| storage temp. | Store at RT |
| CAS DataBase Reference | 184475-35-2(CAS DataBase Reference) |
| Safety Information |
| Gefitinib Usage And Synthesis |
| Chemical Properties | Light-Yellow Crystalline Powder |
| Usage | Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. |
| Usage | Gefitinib is an antineoplastic. |
| Biological Activity | Orally active, selective inhibitor of EGFR tyrosine kinase (IC 50 = 23-79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts. |