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Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)- CAS NO.87-11-6
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,MoneyGram,Other
- Product Details
Keywords
- Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-? price
- Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-? CAS 87-11-6
- Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-? supplier in China
Quick Details
- ProName: Acetamide,N-(4,5-dihydro-4-methyl-5-ox...
- CasNo: 87-11-6
- Molecular Formula: C8H8 N2 O2 S2?
- Appearance: Yellow solid
- Application: antitumour activity. Thiolutin is a po...
- DeliveryTime: 15 days after order confirmed
- PackAge: 1kg/bag, 1kg/drum or 25kg/drum or as p...
- Port: Shanghai, Ningbo, Tianjin, etc
- ProductionCapacity: 1 Metric Ton/Month
- Purity: 99%
- Storage: Stored in cool, dry and ventilation pl...
- Transportation: as per your request
- LimitNum: 1 Kilogram
Superiority
superior quality
Details
| THIOLUTIN Chemical Properties |
| storage temp. | −20°C |
| solubility | DMSO: 5 mg/mL |
| Safety Information |
| Hazard Codes | T+,T |
| Risk Statements | 28 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | JP1355000 |
| THIOLUTIN Usage And Synthesis |
| Chemical Properties | Yellow solid |
| Usage | Thiolutin is an antibiotic first described by Tanner and co-workers in 1950. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumour activity. Thiolutin is a potent inhibitor of bacterial and yeast RNA polymerases, and also inhibits mannan and glucan formation in fungi. Thiolutin suppresses tumour cell-induced angiogenesis in vivo. |
| Usage | Thiolutin is an antibiotic isolated from several strains of Streptomyces albus. Thiolutin is a natural dithiol that reversibly inhibits bacterial and yeast RNA polymerases. |
| Biological Activity | Antibiotic; inhibits bacterial RNA polymerase. Inhibits adhesion of HUVEC cells to vitronectin (IC 50 = 0.83 mM) and subsequently reduces paxillin levels. Suppresses tumor cell-induced angiogenesis. |